KMID : 0387720070180010009
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Korean Journal of Blood Transfusion 2007 Volume.18 No. 1 p.9 ~ p.14
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The Usage of Uncrossmatched Group O, Rh-Negative RBCs for Emergency Transfusion
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Park Seo-Jin
Bae In-Cheol Park Youn-Hee Park In-Cheol Kim Seung-Ho Kim Hyun-Ok
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Abstract
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Background:The use of uncrossmatched group O, Rh-negative RBCs has enabled immediate transfusion of patients who need critical care in life-threatening situations. We examined our 1-year experience with uncrossmatched group O, Rh-negative RBC transfusion in a tertiary care university hospital.
Method: Uncrossmatched group O, Rh-negative RBCs were available for immediate transfusion upon request without performing any of the following pretransfusion tests: ABO and RhD typing, irregular antibody screening, crossmatching test. The characteristics of the transfused patients were studied retrospectively.
Results: Twenty-five patients received 56 units of uncrossmatched group O, Rh-negative RBCs from November 2005 to October 2006. An average of 2.24 units was issued to each patient, with no more than 4 units per patient being given; subsequent transfusion was done with type-specific, crossmatched blood. The average turnaround time for the release of uncrossmatched group O, Rh-negative RBCs was 1.8 minutes (mean?standard deviation: 1.8?1.96, range: 0¡7 minutes). Seventeen patients died (68%), which included 16 patients who had received cardiopulmonary resuscitation.
Conclusions: Patients admitted for traffic accident, falling down injury, gastrointestinal bleeding and aortic dissection received 72% of the emergency group O, Rh-negative RBCs, with a 72.2% mortality rate, which indicates the dire condition of these patients. The majority of RBCs for transfusion were available within 5 minutes upon request. Though group O, Rh-negative RBCs are recommended in emergency situations in which the blood group of the patient is unknown, the use of group O, Rh-positive RBCs may be an alternative blood supply, when considering the short supply of Rh-negative RBCs.
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KEYWORD
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Emergency transfusion, Uncrossmatched blood, Group O Rh-negative RBC transfusion
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